We are looking for highly motivated PhD students/doctoral students (f/m/d) to join a team of researchers from Berlin, Bremen, Magdeburg and Haifa for a project dealing with synaptic autophagy funded by the DFG - FOR5228 Syntophagy “Membrane trafficking processes underlying presynaptic proteostasis”. The posts are available initially for a 3-year fixed-term period with a salary of TV-L E13 (65%) starting latest January 1st 2022.

Congratulations to our PhD student Sebastian Samer for winning the LIN Seeds project funding in the Doctoral student category!

Our paper on missense mutations in Shank3 is published in eLife. Great collaboration with the labs of Eunjoon and Marina

Exciting news! Alzheimer Forschung Initiative will fund Kasia's pilot research on the mechanisms of neuroinflammatory properties of posttranslationally modified amyloid beta

12th of January 2021, a paper published in Molecular Brain

19th of December 2020, a paper published in Cellular and Molecular Life Sciences

26.11.2020 Exciting news! DFG will fund our CRC 1436 initiative "Neural Resources of Cognition". More than 20 outstanding projects will be funded! Great news for the Magdeburg neuroscience community.

25.11.20 We are happy that Alexandre Ryzynski has joined us as a PhD student. Welcome to Nplast, Alexandre!

9.06.20 - Irene Reyes Resina got the LIN Seeds funding in the postdoc category. Congratulations, Irene!

1.03.20 - We are happy that Anja Oelschlegel has joined us. Welcome to NPlast, Anja!.

25.02.20 - We had the pleasure to chat and show a bit of what we do at NPlast to a neuroscience living legend, one of the discoverers of LTP, Tim Bliss.

9.12.19 - Daniel Giffney joined NPlast for his internship. Welcome to NPlast, Dan!

29th of November 2019, a paper published in Nature Communications. - Thank you all for the input!

• Image idea - Anna Karpova, • Image courtesy – Dorothea Hertel

19.11.2019 - Alessandro D. Confettura defended his Ph.D thesis. Congratulation, Alessandro!

30.09.19 - We are looking for a Ph.D. student in a joint project to study autophagy in axons of LC neurons

17.06.2019 - Marie Oulé defended her Ph.D. thesis. Congratulations, Marie!

Sebastian Samer got the first prize for the Best Talk at the Institute retreat (4.06.2019). Well done, Sebastian!

We are happy that Irene, Vsevolod and Eleonora have joined us. Welcome to NPlast!

The new Research Training Group 2413 “SynAGE” funded by the DFG (Deutsche Forschungsgemeinschaft) started on January 1st, 2019

The innovative research program of RTG2413 SynAGE deals with the idea that cognitive decline in normal aging results from subtle synaptic alterations that impart an imbalance between stability and plastic properties of spine synapses and that is qualitatively different from neurodegeneration. Despite the high burden for each individual and the society as a whole the molecular, cellular, and behavioral underpinnings of the ageing process itself and cognitive decline are barely understood. We will concentrate on synaptic dysbalances involving these four core principles:

• altered synaptic proteostasis (Dieterich Lab, Stork Lab, Kreutz Lab)

• dysfunctions of the immune system (Kreutz Lab, Dunay Lab)

• altered functionality of the multipartite synapse (Dityatev Lab, Schreiber Lab, Gundelfinger Lab, Seidenbecher Lab, Dieterich Lab)

• changes in neuromodulation (Leßmann Lab, Stork Lab, Düzel Lab, Ullsperger Lab)

SynAGE will address these four transversal themes in a joint effort by a team of molecular/cellular and systems neurobiologists to eventually break ground for innovative intervention strategies.

DOF in Hamburg joined in January the DFG-funded FOR 2419: Plasticity versus Stability - Molecular Mechanisms of Synaptic Strength at the Center for Molecular Neurobiology in Hamburg

We will contribute a project on “The needs of a synapse - how local microsecretory systems and organelles serve synaptic function”. Kim, Max and Maru teaming up to address this question.

14 June 2018 - Ioana defended her PhD thesis. Congratulations!

18 April 2018 - NPlast publishes paper in Cerebral Cortex. The team of Jeffrey with Mael as first author could show that the T-type calcium channel Cav3.2, at the axon initial segment of mature granule cells, modulates the efficacy of the dentate-to-CA3 communication by influencing the pattern of action potentials elicited by mature granule cells.

19 April 2018 - Mael defended his PhD thesis. Congratulations!

15 March 2018 - Kasia defended her PhD thesis. Congratulations!

20 February 2018 - NPlast publishes paper in Neuron . Great team effort! Many thanks to all for the input.

13th of November 2017 - Gonca defended her thesis. Congratulations!!!